Paul joined the laboratory in 2018 as a graduate student in the BME PhD program after graduating Magna Cum Laude with BS in Electrical Engineering from Univ. of Washington, where he was a Mary Gates Research Scholar.
Paul's research focused on understanding the neural basis of movement control by the cerebellum, particularly control of the tongue. He designed the image guided procedures for 3D printed parts that we use in our marmoset research, which allow for precise targetting of cerebellar regions. He led the team of students that investigated the role of the cerebellum in control of tongue movements. He was the first person to record from the marmoset lingual cerebellum, discovering that the function of this region was to produces forces that would retract the tongue, playing a fundamental role in stopping the movements of the tongue as it approaches its target.
Paul graduated in 2024 and subsequently joined the Johns Hopkins Applied Physics Laboratory.
Lectures by Paul:
Shoup, Alden M., Natasha Porwal, Mohammad Amin Fakharian, Paul Hage, Simon P. Orozco, and Reza Shadmehr. "Rejuvenating silicon probes for acute neurophysiology." Journal of Neurophysiology (2024).
Pi, J. S., Fakharian, M. A., Hage, P., Sedaghat-Nejad, E., Muller, S. Z., & Shadmehr, R. (2024). The olivary input to the cerebellum dissociates sensory events from movement plans. Proceedings of the National Academy of Sciences, 121(17), e2318849121.
Hage, Paul, In Kyu Jang, Vivian Looi, Mohammad Amin Fakharian, Simon P. Orozco, Jay S. Pi, Ehsan Sedaghat-Nejad, and Reza Shadmehr. Effort cost of harvest affects decisions and movement vigor of marmosets during foraging. Elife 12 (2023): RP87238.
Muller, S. Z., Pi, J. S., Hage, P., Fakharian, M. A., Sedaghat-Nejad, E., & Shadmehr, R. (2023). Complex spikes perturb movements and reveal the sensorimotor map of Purkinje cells. Current Biology, 33(22), 4869-4879.
Sedaghat-Nejad E, Herzfeld DJ*, Hage P*, Karbasi K, Palin T, Wang X., and Shadmehr R (2019) Behavioral training of marmosets and electrophysiological recording from the cerebellum. Journal of Neurophysiology.
E Sedaghat-Nejad, JS Pi, P Hage, MA Fakharian, R Shadmehr (2022)
Synchronous spiking of cerebellar Purkinje cells during control of movements. Proceedings of the National Academy of Sciences 119 (14), e2118954119.
Synchronous spiking of cerebellar Purkinje cells during control of movements. Proceedings of the National Academy of Sciences 119 (14), e2118954119.
Ehsan Sedaghat-Nejad, Mohammad Amin Fakharian, Jay Pi, Paul Hage, Yoshiko Kojima, Robi Soetedjo, Shogo Ohmae, Javier F Medina, Reza Shadmehr (2021) P-sort: an open-source software for cerebellar neurophysiology. Journal of Neurophysiology 126 (4), 1055-1075.
Hage, Paul, In Kyu Jang, Vivian Looi, Mohammad Amin Fakharian, Simon P. Orozco, Jay S. Pi, Ehsan Sedaghat-Nejad, and Reza Shadmehr. "Effort cost of harvest affects decisions and movement vigor of marmosets during foraging." eLife, 2023.
Sedaghat-Nejad, Ehsan, Jay S. Pi, Paul Hage, Mohammad Amin Fakharian, and Reza Shadmehr. "Synchronous spiking of cerebellar Purkinje cells during control of movements." Proceedings of the National Academy of Sciences 119, no. 14 (2022): e2118954119.
Publications
Publications
Paul Hage
Paul Hage
